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About avapro (Irbesartan)

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What are irbesartan tablets?

IRBESARTAN (Avapro reg;) helps lower blood pressure to normal levels. It controls high blood pressure, but it is not a cure. High blood pressure can damage your kidneys, and may lead to a stroke or heart failure. Irbesartan helps prevent these things from happening.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat
heart failure
kidney disease
liver disease
electrolyte imbalance (e.g. low or high levels of potassium in the blood)
if you are on a special diet, such as a low-salt diet (e.g. using potassium substitutes)
an unusual or allergic reaction to irbesartan, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding

How should I take this medicine?

Take irbesartan tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Irbesartan can be taken with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with irbesartan?

antiinflammatory pain medicines such as ibuprofen (Motrin reg;)
blood pressure medications
bosentan
delavirdine
imatinib
fluconazole
hawthorn
lithium
monoamine oxidase inhibitors (Azilect reg;, Eldepryl reg;, Emsam reg;, Marplan reg;, Nardil reg;, Parnate reg;, Zelapar trade;)
potassium salts or potassium supplements
rifampin
voriconazole
water pills (especially potassium-sparing diuretics such as triamterene or amiloride)

Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking irbesartan?

Side effects that you should report to your prescriber or health care professional as soon as possible:

Rare or uncommon:

difficulty breathing or swallowing, hoarseness, or tightening of the throat
swelling of your face, lips, tongue, hands, or feet
unusual rash or hives
decreased sexual function

Other:

confusion, dizziness, lightheadedness or fainting spells
decreased amount of urine passed
fast or uneven heart beat or palpitations

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

cough
diarrhea
fatigue or tiredness
nasal congestion or stuffiness
sore or cramping muscles
upset stomach

What should I watch for while taking irbesartan?

Check your blood pressure regularly while you are taking irbesartan. Ask your prescriber or health care professional what your blood pressure should be and when you should contact him or her. When you check your blood pressure, write down the measurements to show your prescriber or health care professional. If you are taking this medicine for a long time you must visit your prescriber or health care professional for regular checks on your progress. Make sure you schedule appointments on a regular basis.

You may experience dizziness. Do not drive, use machinery, or do anything that requires mental alertness until you know how irbesartan affects you. To avoid dizziness, do not stand or sit up quickly.

Avoid salt substitutes unless you are told otherwise by your prescriber or health care professional.

If you are going to have surgery tell your prescriber or health care professional that you are taking irbesartan.

Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child, particularly in the second or third trimester. Talk to your health care professional or pharmacist for more information.

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